Cargando…

Making of Viral Replication Organelles by Remodeling Interior Membranes

Positive-stranded RNA (+RNA) viruses exploit host cell machinery by subverting host proteins and membranes and altering cellular pathways during infection. To achieve robust replication, some +RNA viruses, such as poliovirus (PV), build special intracellular compartments, called viral replication or...

Descripción completa

Detalles Bibliográficos
Autores principales: Sasvari, Zsuzsanna, Nagy, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185585/
https://www.ncbi.nlm.nih.gov/pubmed/21994625
http://dx.doi.org/10.3390/v2112436
_version_ 1782213237736996864
author Sasvari, Zsuzsanna
Nagy, Peter D.
author_facet Sasvari, Zsuzsanna
Nagy, Peter D.
author_sort Sasvari, Zsuzsanna
collection PubMed
description Positive-stranded RNA (+RNA) viruses exploit host cell machinery by subverting host proteins and membranes and altering cellular pathways during infection. To achieve robust replication, some +RNA viruses, such as poliovirus (PV), build special intracellular compartments, called viral replication organelles. A recent work from the Altan-Bonnett laboratory [1] gave new insights into the formation of poliovirus replication organelles, which are unique subcellular structures containing many individual replication complexes as a result of dynamic cellular membrane remodeling.
format Online
Article
Text
id pubmed-3185585
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Molecular Diversity Preservation International (MDPI)
record_format MEDLINE/PubMed
spelling pubmed-31855852011-10-12 Making of Viral Replication Organelles by Remodeling Interior Membranes Sasvari, Zsuzsanna Nagy, Peter D. Viruses Commentary Positive-stranded RNA (+RNA) viruses exploit host cell machinery by subverting host proteins and membranes and altering cellular pathways during infection. To achieve robust replication, some +RNA viruses, such as poliovirus (PV), build special intracellular compartments, called viral replication organelles. A recent work from the Altan-Bonnett laboratory [1] gave new insights into the formation of poliovirus replication organelles, which are unique subcellular structures containing many individual replication complexes as a result of dynamic cellular membrane remodeling. Molecular Diversity Preservation International (MDPI) 2010-11-05 /pmc/articles/PMC3185585/ /pubmed/21994625 http://dx.doi.org/10.3390/v2112436 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Commentary
Sasvari, Zsuzsanna
Nagy, Peter D.
Making of Viral Replication Organelles by Remodeling Interior Membranes
title Making of Viral Replication Organelles by Remodeling Interior Membranes
title_full Making of Viral Replication Organelles by Remodeling Interior Membranes
title_fullStr Making of Viral Replication Organelles by Remodeling Interior Membranes
title_full_unstemmed Making of Viral Replication Organelles by Remodeling Interior Membranes
title_short Making of Viral Replication Organelles by Remodeling Interior Membranes
title_sort making of viral replication organelles by remodeling interior membranes
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185585/
https://www.ncbi.nlm.nih.gov/pubmed/21994625
http://dx.doi.org/10.3390/v2112436
work_keys_str_mv AT sasvarizsuzsanna makingofviralreplicationorganellesbyremodelinginteriormembranes
AT nagypeterd makingofviralreplicationorganellesbyremodelinginteriormembranes