A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission

Retroviruses like HIV-1 and HTLV-1 can be transmitted efficiently by direct contact between infected and target cells. For HIV-1, various modes of cell-to-cell transfer have been reported, including virological synapses, polysynapses, filopodial bridges, and nanotube-like structures. So far, only sy...

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Detalles Bibliográficos
Autores principales: Malbec, Marine, Roesch, Ferdinand, Schwartz, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185692/
https://www.ncbi.nlm.nih.gov/pubmed/21994729
http://dx.doi.org/10.3390/v3030254
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author Malbec, Marine
Roesch, Ferdinand
Schwartz, Olivier
author_facet Malbec, Marine
Roesch, Ferdinand
Schwartz, Olivier
author_sort Malbec, Marine
collection PubMed
description Retroviruses like HIV-1 and HTLV-1 can be transmitted efficiently by direct contact between infected and target cells. For HIV-1, various modes of cell-to-cell transfer have been reported, including virological synapses, polysynapses, filopodial bridges, and nanotube-like structures. So far, only synapses and biofilms have been described for HTLV-1 transmission. Recently, Van Prooyen et al. [1] identified an additional mode of HTLV-1 transmission through cellular conduits induced by the viral accessory protein p8.
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spelling pubmed-31856922011-10-12 A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission Malbec, Marine Roesch, Ferdinand Schwartz, Olivier Viruses Commentary Retroviruses like HIV-1 and HTLV-1 can be transmitted efficiently by direct contact between infected and target cells. For HIV-1, various modes of cell-to-cell transfer have been reported, including virological synapses, polysynapses, filopodial bridges, and nanotube-like structures. So far, only synapses and biofilms have been described for HTLV-1 transmission. Recently, Van Prooyen et al. [1] identified an additional mode of HTLV-1 transmission through cellular conduits induced by the viral accessory protein p8. Molecular Diversity Preservation International (MDPI) 2011-03-09 /pmc/articles/PMC3185692/ /pubmed/21994729 http://dx.doi.org/10.3390/v3030254 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Commentary
Malbec, Marine
Roesch, Ferdinand
Schwartz, Olivier
A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission
title A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission
title_full A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission
title_fullStr A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission
title_full_unstemmed A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission
title_short A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission
title_sort new role for the htlv-1 p8 protein: increasing intercellular conduits and viral cell-to-cell transmission
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185692/
https://www.ncbi.nlm.nih.gov/pubmed/21994729
http://dx.doi.org/10.3390/v3030254
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