Cargando…

A Strong Case for Viral Genetic Factors in HIV Virulence

HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four studies [1–4] published within a year has filled this important gap and has demonstrated a robust...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller, Viktor, Fraser, Christophe, Herbeck, Joshua T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185695/
https://www.ncbi.nlm.nih.gov/pubmed/21994727
http://dx.doi.org/10.3390/v3030204
_version_ 1782213249539768320
author Müller, Viktor
Fraser, Christophe
Herbeck, Joshua T.
author_facet Müller, Viktor
Fraser, Christophe
Herbeck, Joshua T.
author_sort Müller, Viktor
collection PubMed
description HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four studies [1–4] published within a year has filled this important gap and has demonstrated a robust effect of the viral genotype on HIV virulence.
format Online
Article
Text
id pubmed-3185695
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Molecular Diversity Preservation International (MDPI)
record_format MEDLINE/PubMed
spelling pubmed-31856952011-10-12 A Strong Case for Viral Genetic Factors in HIV Virulence Müller, Viktor Fraser, Christophe Herbeck, Joshua T. Viruses Commentary HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four studies [1–4] published within a year has filled this important gap and has demonstrated a robust effect of the viral genotype on HIV virulence. Molecular Diversity Preservation International (MDPI) 2011-03-08 /pmc/articles/PMC3185695/ /pubmed/21994727 http://dx.doi.org/10.3390/v3030204 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Commentary
Müller, Viktor
Fraser, Christophe
Herbeck, Joshua T.
A Strong Case for Viral Genetic Factors in HIV Virulence
title A Strong Case for Viral Genetic Factors in HIV Virulence
title_full A Strong Case for Viral Genetic Factors in HIV Virulence
title_fullStr A Strong Case for Viral Genetic Factors in HIV Virulence
title_full_unstemmed A Strong Case for Viral Genetic Factors in HIV Virulence
title_short A Strong Case for Viral Genetic Factors in HIV Virulence
title_sort strong case for viral genetic factors in hiv virulence
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185695/
https://www.ncbi.nlm.nih.gov/pubmed/21994727
http://dx.doi.org/10.3390/v3030204
work_keys_str_mv AT mullerviktor astrongcaseforviralgeneticfactorsinhivvirulence
AT fraserchristophe astrongcaseforviralgeneticfactorsinhivvirulence
AT herbeckjoshuat astrongcaseforviralgeneticfactorsinhivvirulence
AT mullerviktor strongcaseforviralgeneticfactorsinhivvirulence
AT fraserchristophe strongcaseforviralgeneticfactorsinhivvirulence
AT herbeckjoshuat strongcaseforviralgeneticfactorsinhivvirulence