Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections(†)

While 25 compounds have been formally licensed for the treatment of HIV infection (AIDS), only seven licensed products are currently available for the treatment of chronic hepatitis B virus (HBV) infection: interferon-α, pegylated interferon-α, lamivudine, adefovir (dipivoxil), entecavir, telbivudin...

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Autores principales: De Clercq, Erik, Férir, Geoffrey, Kaptein, Suzanne, Neyts, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185710/
https://www.ncbi.nlm.nih.gov/pubmed/21994680
http://dx.doi.org/10.3390/v2061279
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author De Clercq, Erik
Férir, Geoffrey
Kaptein, Suzanne
Neyts, Johan
author_facet De Clercq, Erik
Férir, Geoffrey
Kaptein, Suzanne
Neyts, Johan
author_sort De Clercq, Erik
collection PubMed
description While 25 compounds have been formally licensed for the treatment of HIV infection (AIDS), only seven licensed products are currently available for the treatment of chronic hepatitis B virus (HBV) infection: interferon-α, pegylated interferon-α, lamivudine, adefovir (dipivoxil), entecavir, telbivudine and tenofovir (disoproxil fumarate). In contrast to the treatment of HIV infections where the individual drugs are routinely used in combination, for the treatment of chronic HBV infection the individual drugs are generally used in monotherapy. In principle, combination drug therapy should allow reducing the likelihood of drug-resistant development.
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spelling pubmed-31857102011-10-12 Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections(†) De Clercq, Erik Férir, Geoffrey Kaptein, Suzanne Neyts, Johan Viruses Review While 25 compounds have been formally licensed for the treatment of HIV infection (AIDS), only seven licensed products are currently available for the treatment of chronic hepatitis B virus (HBV) infection: interferon-α, pegylated interferon-α, lamivudine, adefovir (dipivoxil), entecavir, telbivudine and tenofovir (disoproxil fumarate). In contrast to the treatment of HIV infections where the individual drugs are routinely used in combination, for the treatment of chronic HBV infection the individual drugs are generally used in monotherapy. In principle, combination drug therapy should allow reducing the likelihood of drug-resistant development. Molecular Diversity Preservation International (MDPI) 2010-05-31 /pmc/articles/PMC3185710/ /pubmed/21994680 http://dx.doi.org/10.3390/v2061279 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
De Clercq, Erik
Férir, Geoffrey
Kaptein, Suzanne
Neyts, Johan
Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections(†)
title Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections(†)
title_full Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections(†)
title_fullStr Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections(†)
title_full_unstemmed Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections(†)
title_short Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections(†)
title_sort antiviral treatment of chronic hepatitis b virus (hbv) infections(†)
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185710/
https://www.ncbi.nlm.nih.gov/pubmed/21994680
http://dx.doi.org/10.3390/v2061279
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