Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report

A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment with tenofovir and persistently undetectable H...

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Autores principales: Schewe, Knud, Noah, Christian, Sirma, Hüseyin, Schmiedel, Stefan, van Lunzen, Jan, Rockstroh, Jürgen Kurt, Schildgen, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Short Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185722/
https://www.ncbi.nlm.nih.gov/pubmed/21994693
http://dx.doi.org/10.3390/v2081564
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author Schewe, Knud
Noah, Christian
Sirma, Hüseyin
Schmiedel, Stefan
van Lunzen, Jan
Rockstroh, Jürgen Kurt
Schildgen, Oliver
author_facet Schewe, Knud
Noah, Christian
Sirma, Hüseyin
Schmiedel, Stefan
van Lunzen, Jan
Rockstroh, Jürgen Kurt
Schildgen, Oliver
author_sort Schewe, Knud
collection PubMed
description A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment with tenofovir and persistently undetectable HBV-DNA viral load for over five years.
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spelling pubmed-31857222011-10-12 Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report Schewe, Knud Noah, Christian Sirma, Hüseyin Schmiedel, Stefan van Lunzen, Jan Rockstroh, Jürgen Kurt Schildgen, Oliver Viruses Short Note A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment with tenofovir and persistently undetectable HBV-DNA viral load for over five years. Molecular Diversity Preservation International (MDPI) 2010-07-29 /pmc/articles/PMC3185722/ /pubmed/21994693 http://dx.doi.org/10.3390/v2081564 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Short Note
Schewe, Knud
Noah, Christian
Sirma, Hüseyin
Schmiedel, Stefan
van Lunzen, Jan
Rockstroh, Jürgen Kurt
Schildgen, Oliver
Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report
title Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report
title_full Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report
title_fullStr Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report
title_full_unstemmed Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report
title_short Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report
title_sort is there emergence of clinical hbv resistance under long-term hbv combination therapy? a challenging case report
topic Short Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185722/
https://www.ncbi.nlm.nih.gov/pubmed/21994693
http://dx.doi.org/10.3390/v2081564
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