Antiviral Strategies for Pandemic and Seasonal Influenza

While vaccines are the primary public health response to seasonal and pandemic flu, short of a universal vaccine there are inherent limitations to this approach. Antiviral drugs provide valuable alternative options for treatment and prophylaxis of influenza. Here, we will review drugs and drug candi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hedlund, Maria, Larson, Jeffrey L., Fang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185731/
https://www.ncbi.nlm.nih.gov/pubmed/21994706
http://dx.doi.org/10.3390/v2081766
_version_ 1782213256178302976
author Hedlund, Maria
Larson, Jeffrey L.
Fang, Fang
author_facet Hedlund, Maria
Larson, Jeffrey L.
Fang, Fang
author_sort Hedlund, Maria
collection PubMed
description While vaccines are the primary public health response to seasonal and pandemic flu, short of a universal vaccine there are inherent limitations to this approach. Antiviral drugs provide valuable alternative options for treatment and prophylaxis of influenza. Here, we will review drugs and drug candidates against influenza with an emphasis on the recent progress of a host-targeting entry-blocker drug candidate, DAS181, a sialidase fusion protein.
format Online
Article
Text
id pubmed-3185731
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Molecular Diversity Preservation International (MDPI)
record_format MEDLINE/PubMed
spelling pubmed-31857312011-10-12 Antiviral Strategies for Pandemic and Seasonal Influenza Hedlund, Maria Larson, Jeffrey L. Fang, Fang Viruses Review While vaccines are the primary public health response to seasonal and pandemic flu, short of a universal vaccine there are inherent limitations to this approach. Antiviral drugs provide valuable alternative options for treatment and prophylaxis of influenza. Here, we will review drugs and drug candidates against influenza with an emphasis on the recent progress of a host-targeting entry-blocker drug candidate, DAS181, a sialidase fusion protein. Molecular Diversity Preservation International (MDPI) 2010-08-20 /pmc/articles/PMC3185731/ /pubmed/21994706 http://dx.doi.org/10.3390/v2081766 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Hedlund, Maria
Larson, Jeffrey L.
Fang, Fang
Antiviral Strategies for Pandemic and Seasonal Influenza
title Antiviral Strategies for Pandemic and Seasonal Influenza
title_full Antiviral Strategies for Pandemic and Seasonal Influenza
title_fullStr Antiviral Strategies for Pandemic and Seasonal Influenza
title_full_unstemmed Antiviral Strategies for Pandemic and Seasonal Influenza
title_short Antiviral Strategies for Pandemic and Seasonal Influenza
title_sort antiviral strategies for pandemic and seasonal influenza
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185731/
https://www.ncbi.nlm.nih.gov/pubmed/21994706
http://dx.doi.org/10.3390/v2081766
work_keys_str_mv AT hedlundmaria antiviralstrategiesforpandemicandseasonalinfluenza
AT larsonjeffreyl antiviralstrategiesforpandemicandseasonalinfluenza
AT fangfang antiviralstrategiesforpandemicandseasonalinfluenza

Ejemplares similares