Multitasking: Making the Most out of the Retroviral Envelope

Evasion of the host’s immune system is a required step for the establishment of viral infection. In this article, we discuss the recent findings of Heidmann and colleagues demonstrating that some retroviruses possess an immune suppressive (IS) domain “encrypted” within their envelope glycoprotein th...

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Detalles Bibliográficos
Autores principales: Varela, Mariana, Palmarini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185736/
https://www.ncbi.nlm.nih.gov/pubmed/21994694
http://dx.doi.org/10.3390/v2081571
Descripción
Sumario:Evasion of the host’s immune system is a required step for the establishment of viral infection. In this article, we discuss the recent findings of Heidmann and colleagues demonstrating that some retroviruses possess an immune suppressive (IS) domain “encrypted” within their envelope glycoprotein that is required to establish a successful infection in immunocompetent hosts [1].

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