A correlative study of Quantitative EMG and biopsy findings in 31 patients with myopathies

A direct correlation of QEMG with muscle biopsy findings might help delineate the sensitivity of QEMG in identifying muscle pathology as well as provide information on electrophysiological- histological correlations. In a study of 31 patients with a variety of myopathies we found that the sensitivit...

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Autores principales: DARDIOTIS, E., PAPATHANASIOU, E., VONTA, I., HADJIGEORGIOU, G., ZAMBA-PAPANICOLAOU, E., KYRIAKIDES, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore SpA 2011
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185837/
https://www.ncbi.nlm.nih.gov/pubmed/21842593
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author DARDIOTIS, E.
PAPATHANASIOU, E.
VONTA, I.
HADJIGEORGIOU, G.
ZAMBA-PAPANICOLAOU, E.
KYRIAKIDES, T.
author_facet DARDIOTIS, E.
PAPATHANASIOU, E.
VONTA, I.
HADJIGEORGIOU, G.
ZAMBA-PAPANICOLAOU, E.
KYRIAKIDES, T.
author_sort DARDIOTIS, E.
collection PubMed
description A direct correlation of QEMG with muscle biopsy findings might help delineate the sensitivity of QEMG in identifying muscle pathology as well as provide information on electrophysiological- histological correlations. In a study of 31 patients with a variety of myopathies we found that the sensitivity of QEMG was between 24 to 69% depending of the specific method of signal analysis. The positive predictive value of abnormal QEMG was more than 90% while its negative predictive value was only about 20%. Amplitude outlier analysis was superior especially in minimally weak muscles (MRC > 4) and was particularly sensitive at detecting increased variability in fiber size and more subtle myopathic changes.
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spelling pubmed-31858372011-11-02 A correlative study of Quantitative EMG and biopsy findings in 31 patients with myopathies DARDIOTIS, E. PAPATHANASIOU, E. VONTA, I. HADJIGEORGIOU, G. ZAMBA-PAPANICOLAOU, E. KYRIAKIDES, T. Acta Myol Original Articles A direct correlation of QEMG with muscle biopsy findings might help delineate the sensitivity of QEMG in identifying muscle pathology as well as provide information on electrophysiological- histological correlations. In a study of 31 patients with a variety of myopathies we found that the sensitivity of QEMG was between 24 to 69% depending of the specific method of signal analysis. The positive predictive value of abnormal QEMG was more than 90% while its negative predictive value was only about 20%. Amplitude outlier analysis was superior especially in minimally weak muscles (MRC > 4) and was particularly sensitive at detecting increased variability in fiber size and more subtle myopathic changes. Pacini Editore SpA 2011-07 /pmc/articles/PMC3185837/ /pubmed/21842593 Text en The journal and the individual contributions contained in it are protected by the copyright of Gaetano Conte Academy, Naples, Italy http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License, which permits for noncommercial use, distribution, and reproduction in any digital medium, provided the original work is properly cited and is not altered in any way. For details, please refer to http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Original Articles
DARDIOTIS, E.
PAPATHANASIOU, E.
VONTA, I.
HADJIGEORGIOU, G.
ZAMBA-PAPANICOLAOU, E.
KYRIAKIDES, T.
A correlative study of Quantitative EMG and biopsy findings in 31 patients with myopathies
title A correlative study of Quantitative EMG and biopsy findings in 31 patients with myopathies
title_full A correlative study of Quantitative EMG and biopsy findings in 31 patients with myopathies
title_fullStr A correlative study of Quantitative EMG and biopsy findings in 31 patients with myopathies
title_full_unstemmed A correlative study of Quantitative EMG and biopsy findings in 31 patients with myopathies
title_short A correlative study of Quantitative EMG and biopsy findings in 31 patients with myopathies
title_sort correlative study of quantitative emg and biopsy findings in 31 patients with myopathies
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185837/
https://www.ncbi.nlm.nih.gov/pubmed/21842593
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