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Anti-addiction vaccines

Despite intensive efforts to eradicate it, addiction to both legal and illicit drugs continues to be a major worldwide medical and social problem. Anti-addiction vaccines can produce the antibodies to block the effects of these drugs on the brain, and have great potential to ameliorate the morbidity...

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Detalles Bibliográficos
Autores principales: Shen, Xiaoyun, Orson, Frank M., Kosten, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186043/
https://www.ncbi.nlm.nih.gov/pubmed/22003367
http://dx.doi.org/10.3410/M3-20
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author Shen, Xiaoyun
Orson, Frank M.
Kosten, Thomas R.
author_facet Shen, Xiaoyun
Orson, Frank M.
Kosten, Thomas R.
author_sort Shen, Xiaoyun
collection PubMed
description Despite intensive efforts to eradicate it, addiction to both legal and illicit drugs continues to be a major worldwide medical and social problem. Anti-addiction vaccines can produce the antibodies to block the effects of these drugs on the brain, and have great potential to ameliorate the morbidity and mortality associated with illicit drug intoxications. This review provides a current overview of anti-addiction vaccines that are under clinical trial and pre-clinical research evaluation. It also outlines the development challenges, ethical concerns, and likely future intervention for anti-addiction vaccines.
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spelling pubmed-31860432011-10-14 Anti-addiction vaccines Shen, Xiaoyun Orson, Frank M. Kosten, Thomas R. F1000 Med Rep Review Article Despite intensive efforts to eradicate it, addiction to both legal and illicit drugs continues to be a major worldwide medical and social problem. Anti-addiction vaccines can produce the antibodies to block the effects of these drugs on the brain, and have great potential to ameliorate the morbidity and mortality associated with illicit drug intoxications. This review provides a current overview of anti-addiction vaccines that are under clinical trial and pre-clinical research evaluation. It also outlines the development challenges, ethical concerns, and likely future intervention for anti-addiction vaccines. Faculty of 1000 Ltd 2011-10-03 /pmc/articles/PMC3186043/ /pubmed/22003367 http://dx.doi.org/10.3410/M3-20 Text en © 2011 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Shen, Xiaoyun
Orson, Frank M.
Kosten, Thomas R.
Anti-addiction vaccines
title Anti-addiction vaccines
title_full Anti-addiction vaccines
title_fullStr Anti-addiction vaccines
title_full_unstemmed Anti-addiction vaccines
title_short Anti-addiction vaccines
title_sort anti-addiction vaccines
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186043/
https://www.ncbi.nlm.nih.gov/pubmed/22003367
http://dx.doi.org/10.3410/M3-20
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