l-Tryptophan-mediated Enhancement of Susceptibility to Nonalcoholic Fatty Liver Disease Is Dependent on the Mammalian Target of Rapamycin

Nonalcoholic fatty liver disease is one of the most common liver diseases. l-Tryptophan and its metabolite serotonin are involved in hepatic lipid metabolism and inflammation. However, it is unclear whether l-tryptophan promotes hepatic steatosis. To explore this issue, we examined the role of l-try...

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Detalles Bibliográficos
Autores principales: Osawa, Yosuke, Kanamori, Hiromitsu, Seki, Ekihiro, Hoshi, Masato, Ohtaki, Hirofumi, Yasuda, Yoichi, Ito, Hiroyasu, Suetsugu, Atsushi, Nagaki, Masahito, Moriwaki, Hisataka, Saito, Kuniaki, Seishima, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186417/
https://www.ncbi.nlm.nih.gov/pubmed/21841000
http://dx.doi.org/10.1074/jbc.M111.235473

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