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Dimebon Does Not Ameliorate Pathological Changes Caused by Expression of Truncated (1–120) Human Alpha-Synuclein in Dopaminergic Neurons of Transgenic Mice
BACKGROUND: Recent clinical studies have demonstrated that dimebon, a drug originally designed and used as a non-selective antihistamine, ameliorates symptoms and delays progress of mild to moderate forms of Alzheimer's and Huntington's diseases. Although the mechanism of dimebon action on...
Autores principales: | Shelkovnikova, Tatyana A., Ustyugov, Alexey A., Millership, Steven, Peters, Owen, Anichtchik, Oleg, Spillantini, Maria Grazia, Buchman, Vladimir L., Bachurin, Sergey O., Ninkina, Natalia N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186720/ https://www.ncbi.nlm.nih.gov/pubmed/21576917 http://dx.doi.org/10.1159/000324989 |
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