Enhanced Th17-Cell Responses Render CCR2-Deficient Mice More Susceptible for Autoimmune Arthritis

CCR2 is considered a proinflammatory mediator in many inflammatory diseases such as rheumatoid arthritis. However, mice lacking CCR2 develop exacerbated collagen-induced arthritis. To explore the underlying mechanism, we investigated whether autoimmune-associated Th17 cells were involved in the path...

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Detalles Bibliográficos
Autores principales: Rampersad, Rishi R., Tarrant, Teresa K., Vallanat, Christopher T., Quintero-Matthews, Tatiana, Weeks, Michael F., Esserman, Denise A., Clark, Jennifer, Di Padova, Franco, Patel, Dhavalkumar D., Fong, Alan M., Liu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186765/
https://www.ncbi.nlm.nih.gov/pubmed/21991368
http://dx.doi.org/10.1371/journal.pone.0025833

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