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The Breadth, but Not the Magnitude, of Circulating Memory B Cell Responses to P. falciparum Increases with Age/Exposure in an Area of Low Transmission

BACKGROUND: Malaria caused by Plasmodium falciparum remains a major cause of death in sub-Saharan Africa. Immunity against symptoms of malaria requires repeated exposure, suggesting either that the parasite is poorly immunogenic or that the development of effective immune responses to malaria may be...

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Detalles Bibliográficos
Autores principales: Nogaro, Sarah I., Hafalla, Julius C., Walther, Brigitte, Remarque, Edmond J., Tetteh, Kevin K. A., Conway, David J., Riley, Eleanor M., Walther, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186790/
https://www.ncbi.nlm.nih.gov/pubmed/21991321
http://dx.doi.org/10.1371/journal.pone.0025582