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The Breadth, but Not the Magnitude, of Circulating Memory B Cell Responses to P. falciparum Increases with Age/Exposure in an Area of Low Transmission
BACKGROUND: Malaria caused by Plasmodium falciparum remains a major cause of death in sub-Saharan Africa. Immunity against symptoms of malaria requires repeated exposure, suggesting either that the parasite is poorly immunogenic or that the development of effective immune responses to malaria may be...
Autores principales: | Nogaro, Sarah I., Hafalla, Julius C., Walther, Brigitte, Remarque, Edmond J., Tetteh, Kevin K. A., Conway, David J., Riley, Eleanor M., Walther, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186790/ https://www.ncbi.nlm.nih.gov/pubmed/21991321 http://dx.doi.org/10.1371/journal.pone.0025582 |
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