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Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

Metformin is the most widely used antidiabetic drug because of its proven efficacy and limited secondary effects. Interestingly, recent studies have reported that metformin can block the growth of different tumor types. Here, we show that metformin exerts antiproliferative effects on melanoma cells,...

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Detalles Bibliográficos
Autores principales: Tomic, T, Botton, T, Cerezo, M, Robert, G, Luciano, F, Puissant, A, Gounon, P, Allegra, M, Bertolotto, C, Bereder, J-M, Tartare-Deckert, S, Bahadoran, P, Auberger, P, Ballotti, R, Rocchi, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186904/
https://www.ncbi.nlm.nih.gov/pubmed/21881601
http://dx.doi.org/10.1038/cddis.2011.86