Cargando…

Improved quality control processing of peptide-centric LC-MS proteomics data

Motivation: In the analysis of differential peptide peak intensities (i.e. abundance measures), LC-MS analyses with poor quality peptide abundance data can bias downstream statistical analyses and hence the biological interpretation for an otherwise high-quality dataset. Although considerable effort...

Descripción completa

Detalles Bibliográficos
Autores principales: Matzke, Melissa M., Waters, Katrina M., Metz, Thomas O., Jacobs, Jon M., Sims, Amy C., Baric, Ralph S., Pounds, Joel G., Webb-Robertson, Bobbie-Jo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187650/
https://www.ncbi.nlm.nih.gov/pubmed/21852304
http://dx.doi.org/10.1093/bioinformatics/btr479