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Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
[Image: see text] Homogeneously glycosylated proteins are important targets for fundamental research and for biopharmaceutical development. The use of unnatural protein–glycan linkages bearing structural similarity to their native counterparts can accelerate the synthesis of glycoengineered proteins...
Autores principales: | Hudak, Jason E., Yu, Helen H., Bertozzi, Carolyn R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187659/ https://www.ncbi.nlm.nih.gov/pubmed/21866965 http://dx.doi.org/10.1021/ja206023e |
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