Restricted Access to Myeloid Cells Explained

The lentiviral accessory protein, Vpx, is known to counteract a restriction factor that is specific to myeloid cells, such as macrophages and dendritic cells. This review summarizes the findings in two seminal studies that identify SAMHD1 as the cellular protein that is responsible for myeloid cell...

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Detalles Bibliográficos
Autor principal: Planelles, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187686/
https://www.ncbi.nlm.nih.gov/pubmed/21994799
http://dx.doi.org/10.3390/v3091624
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author Planelles, Vicente
author_facet Planelles, Vicente
author_sort Planelles, Vicente
collection PubMed
description The lentiviral accessory protein, Vpx, is known to counteract a restriction factor that is specific to myeloid cells, such as macrophages and dendritic cells. This review summarizes the findings in two seminal studies that identify SAMHD1 as the cellular protein that is responsible for myeloid cell restriction, and establish the existence of other types of restriction in these cells.
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spelling pubmed-31876862011-10-12 Restricted Access to Myeloid Cells Explained Planelles, Vicente Viruses Commentary The lentiviral accessory protein, Vpx, is known to counteract a restriction factor that is specific to myeloid cells, such as macrophages and dendritic cells. This review summarizes the findings in two seminal studies that identify SAMHD1 as the cellular protein that is responsible for myeloid cell restriction, and establish the existence of other types of restriction in these cells. Molecular Diversity Preservation International (MDPI) 2011-09-05 /pmc/articles/PMC3187686/ /pubmed/21994799 http://dx.doi.org/10.3390/v3091624 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Commentary
Planelles, Vicente
Restricted Access to Myeloid Cells Explained
title Restricted Access to Myeloid Cells Explained
title_full Restricted Access to Myeloid Cells Explained
title_fullStr Restricted Access to Myeloid Cells Explained
title_full_unstemmed Restricted Access to Myeloid Cells Explained
title_short Restricted Access to Myeloid Cells Explained
title_sort restricted access to myeloid cells explained
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187686/
https://www.ncbi.nlm.nih.gov/pubmed/21994799
http://dx.doi.org/10.3390/v3091624
work_keys_str_mv AT planellesvicente restrictedaccesstomyeloidcellsexplained

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