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TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle
Mitotic spindle assembly requires the regulated activity of numerous spindle-associated proteins. In mammalian cells, the Kinesin-5 motor Eg5 interacts with the spindle assembly factor TPX2, but how this interaction contributes to spindle formation and function is not established. Using bacterial ar...
Autores principales: | Ma, Nan, Titus, Janel, Gable, Alyssa, Ross, Jennifer L., Wadsworth, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187703/ https://www.ncbi.nlm.nih.gov/pubmed/21969468 http://dx.doi.org/10.1083/jcb.201106149 |
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