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Functional Connection between Rad51 and PML in Homology-Directed Repair

The promyelocytic leukemia protein (PML) is a tumor suppressor critical for formation of nuclear bodies (NBs) performing important functions in transcription, apoptosis, DNA repair and antiviral responses. Earlier studies demonstrated that simian virus 40 (SV40) initiates replication near PML NBs. H...

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Detalles Bibliográficos
Autores principales: Boichuk, Sergei, Hu, Liang, Makielski, Kathleen, Pandolfi, Pier Paolo, Gjoerup, Ole V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187806/
https://www.ncbi.nlm.nih.gov/pubmed/21998700
http://dx.doi.org/10.1371/journal.pone.0025814