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Human Glial-Restricted Progenitor Transplantation into Cervical Spinal Cord of the SOD1(G93A) Mouse Model of ALS
Cellular abnormalities are not limited to motor neurons in amyotrophic lateral sclerosis (ALS). There are numerous observations of astrocyte dysfunction in both humans with ALS and in SOD1(G93A) rodents, a widely studied ALS model. The present study therapeutically targeted astrocyte replacement in...
Autores principales: | Lepore, Angelo C., O'Donnell, John, Kim, Andrew S., Williams, Timothy, Tuteja, Alicia, Rao, Mahendra S., Kelley, Linda L., Campanelli, James T., Maragakis, Nicholas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187829/ https://www.ncbi.nlm.nih.gov/pubmed/21998733 http://dx.doi.org/10.1371/journal.pone.0025968 |
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