Integration-Free iPS Cells Engineered Using Human Artificial Chromosome Vectors

Human artificial chromosomes (HACs) have unique characteristics as gene-delivery vectors, including episomal transmission and transfer of multiple, large transgenes. Here, we demonstrate the advantages of HAC vectors for reprogramming mouse embryonic fibroblasts (MEFs) into induced pluripotent stem...

Descripción completa

Detalles Bibliográficos
Autores principales: Hiratsuka, Masaharu, Uno, Narumi, Ueda, Kana, Kurosaki, Hajime, Imaoka, Natsuko, Kazuki, Kanako, Ueno, Etsuya, Akakura, Yutaro, Katoh, Motonobu, Osaki, Mitsuhiko, Kazuki, Yasuhiro, Nakagawa, Masato, Yamanaka, Shinya, Oshimura, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187830/
https://www.ncbi.nlm.nih.gov/pubmed/21998730
http://dx.doi.org/10.1371/journal.pone.0025961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187830/
https://www.ncbi.nlm.nih.gov/pubmed/21998730
http://dx.doi.org/10.1371/journal.pone.0025961

Ejemplares similares