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Integration-Free iPS Cells Engineered Using Human Artificial Chromosome Vectors

Human artificial chromosomes (HACs) have unique characteristics as gene-delivery vectors, including episomal transmission and transfer of multiple, large transgenes. Here, we demonstrate the advantages of HAC vectors for reprogramming mouse embryonic fibroblasts (MEFs) into induced pluripotent stem...

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Detalles Bibliográficos
Autores principales:	Hiratsuka, Masaharu, Uno, Narumi, Ueda, Kana, Kurosaki, Hajime, Imaoka, Natsuko, Kazuki, Kanako, Ueno, Etsuya, Akakura, Yutaro, Katoh, Motonobu, Osaki, Mitsuhiko, Kazuki, Yasuhiro, Nakagawa, Masato, Yamanaka, Shinya, Oshimura, Mitsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187830/ https://www.ncbi.nlm.nih.gov/pubmed/21998730 http://dx.doi.org/10.1371/journal.pone.0025961

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