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Leveraging the power of next-generation sequencing to generate interactome datasets
Next-generation sequencing (NGS) has not been applied to protein-protein interactome network mapping so far because the association between the members of each interacting pair would not be maintained in en masse sequencing. We describe a massively parallel interactome-mapping pipeline, “Stitch-Seq”...
Autores principales: | Yu, Haiyuan, Tardivo, Leah, Tam, Stanley, Weiner, Evan, Gebreab, Fana, Fan, Changyu, Svrzikapa, Nenad, Hirozane-Kishikawa, Tomoko, Rietman, Edward, Yang, Xinping, Sahalie, Julie, Salehi-Ashtiani, Kourosh, Hao, Tong, Cusick, Michael E., Hill, David E., Roth, Frederick P., Braun, Pascal, Vidal, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188388/ https://www.ncbi.nlm.nih.gov/pubmed/21516116 http://dx.doi.org/10.1038/nmeth.1597 |
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