Cargando…

Fumarate Reductase Activity Maintains an Energized Membrane in Anaerobic Mycobacterium tuberculosis

Oxygen depletion of Mycobacterium tuberculosis engages the DosR regulon that coordinates an overall down-regulation of metabolism while up-regulating specific genes involved in respiration and central metabolism. We have developed a chemostat model of M. tuberculosis where growth rate was a function...

Descripción completa

Detalles Bibliográficos
Autores principales: Watanabe, Shinya, Zimmermann, Michael, Goodwin, Michael B., Sauer, Uwe, Barry, Clifton E., Boshoff, Helena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188519/
https://www.ncbi.nlm.nih.gov/pubmed/21998585
http://dx.doi.org/10.1371/journal.ppat.1002287