Critical Roles for LIGHT and Its Receptors in Generating T Cell-Mediated Immunity during Leishmania donovani Infection

LIGHT (TNFSF14) is a member of the TNF superfamily involved in inflammation and defence against infection. LIGHT signals via two cell-bound receptors; herpes virus entry mediator (HVEM) and lymphotoxin-beta receptor (LTβR). We found that LIGHT is critical for control of hepatic parasite growth in mi...

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Detalles Bibliográficos
Autores principales: Stanley, Amanda C., de Labastida Rivera, Fabian, Haque, Ashraful, Sheel, Meru, Zhou, Yonghong, Amante, Fiona H., Bunn, Patrick T., Randall, Louise M., Pfeffer, Klaus, Scheu, Stefanie, Hickey, Michael J., Saunders, Bernadette M., Ware, Carl, Hill, Geoff R., Tamada, Koji, Kaye, Paul M., Engwerda, Christian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188526/
https://www.ncbi.nlm.nih.gov/pubmed/21998581
http://dx.doi.org/10.1371/journal.ppat.1002279

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