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A Barcode Screen for Epigenetic Regulators Reveals a Role for the NuB4/HAT-B Histone Acetyltransferase Complex in Histone Turnover
Dynamic modification of histone proteins plays a key role in regulating gene expression. However, histones themselves can also be dynamic, which potentially affects the stability of histone modifications. To determine the molecular mechanisms of histone turnover, we developed a parallel screening me...
Autores principales: | Verzijlbergen, Kitty F., van Welsem, Tibor, Sie, Daoud, Lenstra, Tineke L., Turner, Daniel J., Holstege, Frank C. P., Kerkhoven, Ron M., van Leeuwen, Fred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188528/ https://www.ncbi.nlm.nih.gov/pubmed/21998594 http://dx.doi.org/10.1371/journal.pgen.1002284 |
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