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Cytoarchitectural disruption of the superior colliculus and an enlarged acoustic startle response in the Tuba1a mutant mouse
The Jenna mutant mouse harbours an S140G mutation in Tuba1a that impairs tubulin heterodimer formation resulting in defective neuronal migration during development. The consequence of decreased neuronal motility is a fractured pyramidal cell layer in the hippocampus and wave-like perturbations in th...
Autores principales: | Edwards, A., Treiber, C.D., Breuss, M., Pidsley, R., Huang, G.-J., Cleak, J., Oliver, P.L., Flint, J., Keays, D.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188702/ https://www.ncbi.nlm.nih.gov/pubmed/21875651 http://dx.doi.org/10.1016/j.neuroscience.2011.08.035 |
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