Endosomal signaling and cell migration

Cell migration is a complex biological process that is under the tight control of diverse signaling events. While many of the involved signaling molecules diffuse rapidly within cells, it now seems that certain key regulators of cell migration prefer to travel on endosomes. In this review we will di...

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Detalles Bibliográficos
Autores principales: Schiefermeier, Natalia, Teis, David, Huber, Lukas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188704/
https://www.ncbi.nlm.nih.gov/pubmed/21546233
http://dx.doi.org/10.1016/j.ceb.2011.04.001
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author Schiefermeier, Natalia
Teis, David
Huber, Lukas A
author_facet Schiefermeier, Natalia
Teis, David
Huber, Lukas A
author_sort Schiefermeier, Natalia
collection PubMed
description Cell migration is a complex biological process that is under the tight control of diverse signaling events. While many of the involved signaling molecules diffuse rapidly within cells, it now seems that certain key regulators of cell migration prefer to travel on endosomes. In this review we will discuss the multiple roles of signaling endosomes in regulation of local migration stimuli, dynamics of focal adhesions, cell contractility and locomotion.
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spelling pubmed-31887042011-10-31 Endosomal signaling and cell migration Schiefermeier, Natalia Teis, David Huber, Lukas A Curr Opin Cell Biol Article Cell migration is a complex biological process that is under the tight control of diverse signaling events. While many of the involved signaling molecules diffuse rapidly within cells, it now seems that certain key regulators of cell migration prefer to travel on endosomes. In this review we will discuss the multiple roles of signaling endosomes in regulation of local migration stimuli, dynamics of focal adhesions, cell contractility and locomotion. Elsevier 2011-10 /pmc/articles/PMC3188704/ /pubmed/21546233 http://dx.doi.org/10.1016/j.ceb.2011.04.001 Text en © 2011 Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/3.0/ Open Access under CC BY-NC-ND 3.0 (https://creativecommons.org/licenses/by-nc-nd/3.0/) license
spellingShingle Article
Schiefermeier, Natalia
Teis, David
Huber, Lukas A
Endosomal signaling and cell migration
title Endosomal signaling and cell migration
title_full Endosomal signaling and cell migration
title_fullStr Endosomal signaling and cell migration
title_full_unstemmed Endosomal signaling and cell migration
title_short Endosomal signaling and cell migration
title_sort endosomal signaling and cell migration
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188704/
https://www.ncbi.nlm.nih.gov/pubmed/21546233
http://dx.doi.org/10.1016/j.ceb.2011.04.001
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