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A statistical framework for modeling gene expression using chromatin features and application to modENCODE datasets
We develop a statistical framework to study the relationship between chromatin features and gene expression. This can be used to predict gene expression of protein coding genes, as well as microRNAs. We demonstrate the prediction in a variety of contexts, focusing particularly on the modENCODE worm...
Autores principales: | Cheng, Chao, Yan, Koon-Kiu, Yip, Kevin Y, Rozowsky, Joel, Alexander, Roger, Shou, Chong, Gerstein, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188797/ https://www.ncbi.nlm.nih.gov/pubmed/21324173 http://dx.doi.org/10.1186/gb-2011-12-2-r15 |
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