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Dating the age of admixture via wavelet transform analysis of genome-wide data
We describe a PCA-based genome scan approach to analyze genome-wide admixture structure, and introduce wavelet transform analysis as a method for estimating the time of admixture. We test the wavelet transform method with simulations and apply it to genome-wide SNP data from eight admixed human popu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188801/ https://www.ncbi.nlm.nih.gov/pubmed/21352535 http://dx.doi.org/10.1186/gb-2011-12-2-r19 |
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author | Pugach, Irina Matveyev, Rostislav Wollstein, Andreas Kayser, Manfred Stoneking, Mark |
author_facet | Pugach, Irina Matveyev, Rostislav Wollstein, Andreas Kayser, Manfred Stoneking, Mark |
author_sort | Pugach, Irina |
collection | PubMed |
description | We describe a PCA-based genome scan approach to analyze genome-wide admixture structure, and introduce wavelet transform analysis as a method for estimating the time of admixture. We test the wavelet transform method with simulations and apply it to genome-wide SNP data from eight admixed human populations. The wavelet transform method offers better resolution than existing methods for dating admixture, and can be applied to either SNP or sequence data from humans or other species. |
format | Online Article Text |
id | pubmed-3188801 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-31888012011-10-07 Dating the age of admixture via wavelet transform analysis of genome-wide data Pugach, Irina Matveyev, Rostislav Wollstein, Andreas Kayser, Manfred Stoneking, Mark Genome Biol Method We describe a PCA-based genome scan approach to analyze genome-wide admixture structure, and introduce wavelet transform analysis as a method for estimating the time of admixture. We test the wavelet transform method with simulations and apply it to genome-wide SNP data from eight admixed human populations. The wavelet transform method offers better resolution than existing methods for dating admixture, and can be applied to either SNP or sequence data from humans or other species. BioMed Central 2011 2011-02-25 /pmc/articles/PMC3188801/ /pubmed/21352535 http://dx.doi.org/10.1186/gb-2011-12-2-r19 Text en Copyright ©2011 Pugach et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Method Pugach, Irina Matveyev, Rostislav Wollstein, Andreas Kayser, Manfred Stoneking, Mark Dating the age of admixture via wavelet transform analysis of genome-wide data |
title | Dating the age of admixture via wavelet transform analysis of genome-wide data |
title_full | Dating the age of admixture via wavelet transform analysis of genome-wide data |
title_fullStr | Dating the age of admixture via wavelet transform analysis of genome-wide data |
title_full_unstemmed | Dating the age of admixture via wavelet transform analysis of genome-wide data |
title_short | Dating the age of admixture via wavelet transform analysis of genome-wide data |
title_sort | dating the age of admixture via wavelet transform analysis of genome-wide data |
topic | Method |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188801/ https://www.ncbi.nlm.nih.gov/pubmed/21352535 http://dx.doi.org/10.1186/gb-2011-12-2-r19 |
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