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A Randomized Placebo-Controlled Phase IIb Trial of A3309, A Bile Acid Transporter Inhibitor, for Chronic Idiopathic Constipation

OBJECTIVES: A3309 is a minimally absorbed ileal bile acid (BA) transporter (IBAT) inhibitor. We conducted an 8-week, multicenter, randomized, double-blind, placebo-controlled, parallel group, phase IIb study, which evaluated A3309 in patients with chronic idiopathic constipation (CIC). METHODS: Pati...

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Detalles Bibliográficos
Autores principales:	Chey, William D, Camilleri, Michael, Chang, Lin, Rikner, Leif, Graffner, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Functional GI Disorders
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188811/ https://www.ncbi.nlm.nih.gov/pubmed/21606974 http://dx.doi.org/10.1038/ajg.2011.162

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