Cargando…

Generation and evaluation of a monoclonal antibody, designated MAdL, as a new specific marker for adenocarcinomas of the lung

BACKGROUND: Different therapy regimens in non-small-cell lung cancer (NSCLC) are of rising clinical importance, and therefore a clear-cut subdifferentiation is mandatory. The common immunohistochemical markers available today are well applicable for subdifferentiation, but a fraction of indistinct c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schultz, H, Marwitz, S, Baron-Lühr, B, Zissel, G, Kugler, C, Rabe, K F, Zabel, P, Vollmer, E, Gerdes, J, Goldmann, T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188931/ https://www.ncbi.nlm.nih.gov/pubmed/21811254 http://dx.doi.org/10.1038/bjc.2011.281

Ejemplares similares

Oesophageal adenocarcinoma is associated with a deregulation in the MYC/MAX/MAD network
por: Boult, J K R, et al.
Publicado: (2008)

Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
por: Goldmann, Torsten, et al.
Publicado: (2018)

Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro
por: Prencipe, M, et al.
Publicado: (2009)

Differences in the histological findings, phenotypic marker expressions and genetic alterations between adenocarcinoma of the gastric cardia and distal stomach
por: Tajima, Y, et al.
Publicado: (2007)

Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma
por: Kobayashi, M, et al.
Publicado: (2012)

Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC
por: Strell, Carina, et al.
Publicado: (2017)

Monoclonal antibody A7-superparamagnetic iron oxide as contrast agent of MR imaging of rectal carcinoma
por: Toma, A, et al.
Publicado: (2005)

Human papillomavirus 16 infection in adenocarcinoma of the cervix
por: Chew, G K, et al.
Publicado: (2005)

Serum biomarker panels for the diagnosis of gastric adenocarcinoma
por: Ahn, H S, et al.
Publicado: (2012)

Desmogleins as prognostic biomarkers in resected pancreatic ductal adenocarcinoma
por: Ormanns, Steffen, et al.
Publicado: (2015)

Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines
por: Prang, N, et al.
Publicado: (2005)

Tumour epithelial vimentin expression and outcome of pancreatic ductal adenocarcinomas
por: Handra-Luca, A, et al.
Publicado: (2011)

Discovery of serum biomarkers for pancreatic adenocarcinoma using proteomic analysis
por: Xue, A, et al.
Publicado: (2010)

mRNA profiling of the cancer degradome in oesophago–gastric adenocarcinoma
por: Baren, J P, et al.
Publicado: (2012)

Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study
por: Aparicio, T, et al.
Publicado: (2013)

MIC-1/GDF15 in Barrett's oesophagus and oesophageal adenocarcinoma
por: Fisher, O M, et al.
Publicado: (2015)

Lymphatic invasion using D2-40 monoclonal antibody and its relationship to lymph node micrometastasis in pN0 gastric cancer
por: Arigami, T, et al.
Publicado: (2005)

HER2 gene copy number status may influence clinical efficacy to anti-EGFR monoclonal antibodies in metastatic colorectal cancer patients
por: Martin, V, et al.
Publicado: (2013)

A UK feasibility and validation study of the VE1 monoclonal antibody immunohistochemistry stain for BRAF-V600E mutations in metastatic melanoma
por: Lo, Michelle Chin I, et al.
Publicado: (2016)

Met expression is an independent prognostic risk factor in patients with oesophageal adenocarcinoma
por: Tuynman, J B, et al.
Publicado: (2008)

Haemoptysis as a prognostic factor in lung adenocarcinoma after curative resection
por: Hu, P, et al.
Publicado: (2013)

Serum microRNA panel as biomarkers for early diagnosis of colorectal adenocarcinoma
por: Zheng, G, et al.
Publicado: (2014)

Comparing computer-generated and pathologist-generated tumour segmentations for immunohistochemical scoring of breast tissue microarrays
por: Akbar, Shazia, et al.
Publicado: (2015)

A humanised anti-IGF-1R monoclonal antibody (AVE1642) enhances Bortezomib-induced apoptosis in myeloma cells lacking CD45
por: Descamps, G, et al.
Publicado: (2009)

Expression of pEGFR and pAKT as response-predictive biomarkers for RAS wild-type patients to anti-EGFR monoclonal antibodies in metastatic colorectal cancers
por: Harlé, A, et al.
Publicado: (2015)

Multi-atlas based detection and localization (MADL) for location-dependent quantification of white matter hyperintensities
por: Wu, Dan, et al.
Publicado: (2019)

Independent prognostic value of fascin immunoreactivity in stage III–IV colonic adenocarcinoma
por: Puppa, G, et al.
Publicado: (2007)

Increasing expression of hypoxia-inducible proteins in the Barrett's metaplasia–dysplasia–adenocarcinoma sequence
por: Griffiths, E A, et al.
Publicado: (2007)

Quantitative expression analysis and prognostic significance of L-DOPA decarboxylase in colorectal adenocarcinoma
por: Kontos, C K, et al.
Publicado: (2010)

Serum apolipoprotein C-II is prognostic for survival after pancreatic resection for adenocarcinoma
por: Xue, A, et al.
Publicado: (2012)

Clinicopathologic and prognostic significance of c-MYC copy number gain in lung adenocarcinomas
por: Seo, A N, et al.
Publicado: (2014)

COUP-TFII regulates metastasis of colorectal adenocarcinoma cells by modulating Snail1
por: Bao, Y, et al.
Publicado: (2014)

Systematic review and meta-analysis of immunohistochemical prognostic biomarkers in resected oesophageal adenocarcinoma
por: McCormick Matthews, L H, et al.
Publicado: (2015)

Cadherin-1 and cadherin-3 cooperation determines the aggressiveness of pancreatic ductal adenocarcinoma
por: Siret, Carole, et al.
Publicado: (2018)

Taurine: a potential marker of apoptosis in gliomas
por: Opstad, K S, et al.
Publicado: (2009)

Proteomic analysis of stage I primary lung adenocarcinoma aimed at individualisation of postoperative therapy
por: Maeda, J, et al.
Publicado: (2008)

Frequent gain of the human telomerase gene TERC at 3q26 in cervical adenocarcinomas
por: Andersson, S, et al.
Publicado: (2006)

Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma
por: Sonobe, M, et al.
Publicado: (2005)

High expression of CXCR4 may predict poor survival in resected pancreatic adenocarcinoma
por: Maréchal, R, et al.
Publicado: (2009)

IGFBP7 is associated with poor prognosis in oesophageal adenocarcinoma and is regulated by promoter DNA methylation
por: Smith, E, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qmj2v3tian7j8sbq0lrjj7ue6a