Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration

BACKGROUND: We investigated prostate involvement during sexually transmitted infections by measuring serum prostate-specific antigen (PSA) as a marker of prostate infection, inflammation, and/or cell damage in young, male US military members. METHODS: We measured PSA before and during infection for...

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Detalles Bibliográficos
Autores principales: Sutcliffe, S, Nevin, R L, Pakpahan, R, Elliott, D J, Cole, S R, De Marzo, A M, Gaydos, C A, Isaacs, W B, Nelson, W G, Sokoll, L J, Zenilman, J M, Cersovsky, S B, Platz, E A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188942/
https://www.ncbi.nlm.nih.gov/pubmed/21792196
http://dx.doi.org/10.1038/bjc.2011.271
Descripción
Sumario:BACKGROUND: We investigated prostate involvement during sexually transmitted infections by measuring serum prostate-specific antigen (PSA) as a marker of prostate infection, inflammation, and/or cell damage in young, male US military members. METHODS: We measured PSA before and during infection for 299 chlamydia, 112 gonorrhoea, and 59 non-chlamydial, non-gonococcal urethritis (NCNGU) cases, and 256 controls. RESULTS: Chlamydia and gonorrhoea, but not NCNGU, cases were more likely to have a large rise (⩾40%) in PSA than controls (33.6%, 19.1%, and 8.2% vs 8.8%, P<0.0001, 0.021, and 0.92, respectively). CONCLUSION: Chlamydia and gonorrhoea may infect the prostate of some infected men.

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