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Suppressing miRNA-15a/-16 expression by interleukin-6 enhances drug-resistance in myeloma cells

The bone marrow microenvironment facilitates the survival, differentiation, and proliferation of myeloma (MM) cells. This study identified that microRNA-15a and -16 expressions tightly correlated with proliferation and drug sensitivity of MM cells. miRNA-15a/-16 expression in MM cells was significan...

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Detalles Bibliográficos
Autores principales: Hao, Mu, Zhang, Li, An, Gang, Sui, Weiwei, Yu, Zhen, Zou, Dehui, Xu , Yan, Chang, Hong, Qiu, Lugui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189173/
https://www.ncbi.nlm.nih.gov/pubmed/21936961
http://dx.doi.org/10.1186/1756-8722-4-37