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Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics
BACKGROUND: Tumor initiating stem-like cells (TISCs) are a subset of neoplastic cells that possess distinct survival mechanisms and self-renewal characteristics crucial for tumor maintenance and propagation. The induction of epithelial-mesenchymal-transition (EMT) by TGFβ has been recently linked to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189192/ https://www.ncbi.nlm.nih.gov/pubmed/21929801 http://dx.doi.org/10.1186/1471-2407-11-396 |