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Translation without eIF2 Promoted by Poliovirus 2A Protease

Poliovirus RNA utilizes eIF2 for the initiation of translation in cell free systems. Remarkably, we now describe that poliovirus translation takes place at late times of infection when eIF2 is inactivated by phosphorylation. By contrast, translation directed by poliovirus RNA is blocked when eIF2 is...

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Detalles Bibliográficos
Autores principales: Redondo, Natalia, Sanz, Miguel Angel, Welnowska, Ewelina, Carrasco, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189197/
https://www.ncbi.nlm.nih.gov/pubmed/22003403
http://dx.doi.org/10.1371/journal.pone.0025699