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IL28B Alleles Exert an Additive Dose Effect When Applied to HCV-HIV Coinfected Persons Undergoing Peginterferon and Ribavirin Therapy

BACKGROUND: Genetic studies have demonstrated a strong association between single nucleotide polymorphisms (SNPs) at IL28B and response to treatment with peginterferon (PEG) and ribavirin (RBV) in HCV monoinfected persons. We sought to test these associations in a prospective PEG / weight based riba...

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Detalles Bibliográficos
Autores principales: Abu Dayyeh, Barham K., Gupta, Namrata, Sherman, Kenneth E., de Bakker, Paul I. W., Chung, Raymond T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189209/
https://www.ncbi.nlm.nih.gov/pubmed/22003405
http://dx.doi.org/10.1371/journal.pone.0025753