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Role of 20-Hydroxyeicosatetraenoic Acid in Mediating Hypertension in Response to Chronic Renal Medullary Endothelin Type B Receptor Blockade

BACKGROUND: The renal medullary endothelin (ET-1) system plays an important role in the control of sodium excretion and arterial pressure (AP) through the activation of renal medullary ET-B receptors. We have previously shown that blockade of endothelin type B receptors (ET-B) leads to salt-sensitiv...

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Detalles Bibliográficos
Autores principales: Speed, Joshua S., George, Eric M., Arany, Marietta, Cockrell, Kathy, Granger, Joey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189228/
https://www.ncbi.nlm.nih.gov/pubmed/22016812
http://dx.doi.org/10.1371/journal.pone.0026063