Cargando…

mGluR5-Antagonist Mediated Reversal of Elevated Stereotyped, Repetitive Behaviors in the VPA Model of Autism

Autism spectrum disorders (ASD) are highly disabling developmental disorders with a population prevalence of 1–3%. Despite a strong genetic etiology, there are no current therapeutic options that target the core symptoms of ASD. Emerging evidence suggests that dysfunction of glutamatergic signaling,...

Descripción completa

Detalles Bibliográficos
Autores principales: Mehta, Mili V., Gandal, Michael J., Siegel, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189241/
https://www.ncbi.nlm.nih.gov/pubmed/22016815
http://dx.doi.org/10.1371/journal.pone.0026077