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DNA Methylation Profiling of Embryonic Stem Cell Differentiation into the Three Germ Layers

Embryogenesis is tightly regulated by multiple levels of epigenetic regulation such as DNA methylation, histone modification, and chromatin remodeling. DNA methylation patterns are erased in primordial germ cells and in the interval immediately following fertilization. Subsequent developmental repro...

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Detalles Bibliográficos
Autores principales: Isagawa, Takayuki, Nagae, Genta, Shiraki, Nobuaki, Fujita, Takanori, Sato, Noriko, Ishikawa, Shumpei, Kume, Shoen, Aburatani, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189249/
https://www.ncbi.nlm.nih.gov/pubmed/22016810
http://dx.doi.org/10.1371/journal.pone.0026052