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DNA Methylation Profiling of Embryonic Stem Cell Differentiation into the Three Germ Layers
Embryogenesis is tightly regulated by multiple levels of epigenetic regulation such as DNA methylation, histone modification, and chromatin remodeling. DNA methylation patterns are erased in primordial germ cells and in the interval immediately following fertilization. Subsequent developmental repro...
Autores principales: | Isagawa, Takayuki, Nagae, Genta, Shiraki, Nobuaki, Fujita, Takanori, Sato, Noriko, Ishikawa, Shumpei, Kume, Shoen, Aburatani, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189249/ https://www.ncbi.nlm.nih.gov/pubmed/22016810 http://dx.doi.org/10.1371/journal.pone.0026052 |
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