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Histoplasma Virulence and Host Responses

Histoplasma capsulatum is the most prevalent cause of fungal respiratory disease. The disease extent and outcomes are the result of the complex interaction between the pathogen and a host's immune system. The focus of our paper consists in presenting the current knowledge regarding the multiple...

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Detalles Bibliográficos
Autores principales: Mihu, Mircea Radu, Nosanchuk, Joshua Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189557/
https://www.ncbi.nlm.nih.gov/pubmed/22007223
http://dx.doi.org/10.1155/2012/268123
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author Mihu, Mircea Radu
Nosanchuk, Joshua Daniel
author_facet Mihu, Mircea Radu
Nosanchuk, Joshua Daniel
author_sort Mihu, Mircea Radu
collection PubMed
description Histoplasma capsulatum is the most prevalent cause of fungal respiratory disease. The disease extent and outcomes are the result of the complex interaction between the pathogen and a host's immune system. The focus of our paper consists in presenting the current knowledge regarding the multiple facets of the dynamic host-pathogen relationship in the context of the virulence arsenal displayed by the fungus and the innate and adaptive immune responses of the host.
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spelling pubmed-31895572011-10-17 Histoplasma Virulence and Host Responses Mihu, Mircea Radu Nosanchuk, Joshua Daniel Int J Microbiol Review Article Histoplasma capsulatum is the most prevalent cause of fungal respiratory disease. The disease extent and outcomes are the result of the complex interaction between the pathogen and a host's immune system. The focus of our paper consists in presenting the current knowledge regarding the multiple facets of the dynamic host-pathogen relationship in the context of the virulence arsenal displayed by the fungus and the innate and adaptive immune responses of the host. Hindawi Publishing Corporation 2012 2011-10-05 /pmc/articles/PMC3189557/ /pubmed/22007223 http://dx.doi.org/10.1155/2012/268123 Text en Copyright © 2012 M. R. Mihu and J. D. Nosanchuk. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Mihu, Mircea Radu
Nosanchuk, Joshua Daniel
Histoplasma Virulence and Host Responses
title Histoplasma Virulence and Host Responses
title_full Histoplasma Virulence and Host Responses
title_fullStr Histoplasma Virulence and Host Responses
title_full_unstemmed Histoplasma Virulence and Host Responses
title_short Histoplasma Virulence and Host Responses
title_sort histoplasma virulence and host responses
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189557/
https://www.ncbi.nlm.nih.gov/pubmed/22007223
http://dx.doi.org/10.1155/2012/268123
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