Fibroblast Growth Factor-2 and the HIV-1 Tat Protein Synergize in Promoting Bcl-2 Expression and Preventing Endothelial Cell Apoptosis: Implications for the Pathogenesis of AIDS-Associated Kaposi's Sarcoma

Kaposi's sarcoma (KS) is a vascular tumor frequently occurring in Human Immunodeficiency Virus- (HIV-) 1-infected individuals. Our previous work indicated that the angiogenic fibroblast growth factor (FGF)-2 and the Tat protein of HIV-1, both expressed in KS lesions of HIV-infected patients, sy...

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Detalles Bibliográficos
Autores principales: Sgadari, Cecilia, Barillari, Giovanni, Palladino, Clelia, Bellino, Stefania, Taddeo, Brunella, Toschi, Elena, Ensoli, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189568/
https://www.ncbi.nlm.nih.gov/pubmed/22007303
http://dx.doi.org/10.1155/2011/452729

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