Experimental Models of Cryptococcosis

Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have...

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Detalles Bibliográficos
Autores principales: Sabiiti, Wilber, May, Robin C., Pursall, E. Rhiannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189605/
https://www.ncbi.nlm.nih.gov/pubmed/22007224
http://dx.doi.org/10.1155/2012/626745
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author Sabiiti, Wilber
May, Robin C.
Pursall, E. Rhiannon
author_facet Sabiiti, Wilber
May, Robin C.
Pursall, E. Rhiannon
author_sort Sabiiti, Wilber
collection PubMed
description Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems.
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spelling pubmed-31896052011-10-17 Experimental Models of Cryptococcosis Sabiiti, Wilber May, Robin C. Pursall, E. Rhiannon Int J Microbiol Review Article Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems. Hindawi Publishing Corporation 2012 2011-10-06 /pmc/articles/PMC3189605/ /pubmed/22007224 http://dx.doi.org/10.1155/2012/626745 Text en Copyright © 2012 Wilber Sabiiti et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sabiiti, Wilber
May, Robin C.
Pursall, E. Rhiannon
Experimental Models of Cryptococcosis
title Experimental Models of Cryptococcosis
title_full Experimental Models of Cryptococcosis
title_fullStr Experimental Models of Cryptococcosis
title_full_unstemmed Experimental Models of Cryptococcosis
title_short Experimental Models of Cryptococcosis
title_sort experimental models of cryptococcosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189605/
https://www.ncbi.nlm.nih.gov/pubmed/22007224
http://dx.doi.org/10.1155/2012/626745
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