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Immunogenicity of a Recombinant Influenza Virus Bearing Both the CD4+ and CD8+ T Cell Epitopes of Ovalbumin

Recombinant influenza viruses that bear the single immunodominant CD8+ T cell epitope OVA(257−264) or the CD4+ T cell epitope OVA(323−339) of the model antigen ovalbumin (OVA) have been useful tools in immunology. Here, we generated a recombinant influenza virus, WSN-OVA(I/II), that bears both OVA-s...

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Detalles Bibliográficos
Autores principales:	Garulli, Bruno, Di Mario, Giuseppina, Sciaraffia, Ester, Kawaoka, Yoshihiro, Castrucci, Maria R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189626/ https://www.ncbi.nlm.nih.gov/pubmed/22007143 http://dx.doi.org/10.1155/2011/497364

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