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Pharmacogenetics of OATP Transporters Reveals That SLCO1B1 c.388A>G Variant Is Determinant of Increased Atorvastatin Response

AIMS: The relationship between variants in SLCO1B1 and SLCO2B1 genes and lipid-lowering response to atorvastatin was investigated. MATERIAL AND METHODS: One-hundred-thirty-six unrelated individuals with hypercholesterolemia were selected and treated with atorvastatin (10 mg/day/4 weeks). They were g...

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Detalles Bibliográficos
Autores principales:	Rodrigues, Alice C., Perin, Paula M. S., Purim, Sheila G., Silbiger, Vivian N., Genvigir, Fabiana D. V., Willrich, Maria Alice V., Arazi, Simone S., Luchessi, Andre D., Hirata, Mario H., Bernik, Marcia M. S., Dorea, Egidio L., Santos, Carla, Faludi, Andre A., Bertolami, Marcelo C., Salas, Antonio, Freire, Ana, Lareu, Maria V., Phillips, Christopher, Porras-Hurtado, Liliana, Fondevila, Manuel, Carracedo, Angel, Hirata, Rosario D. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189752/ https://www.ncbi.nlm.nih.gov/pubmed/22016628 http://dx.doi.org/10.3390/ijms12095815

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