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BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

BACKGROUND: Colorectal cancer is a common disease that involves genetic alterations, such as inactivation of tumour suppressor genes and activation of oncogenes. Among them are RAS and BRAF mutations, which rarely coexist in the same tumour. Individual members of the Rho (Ras homology) GTPases contr...

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Detalles Bibliográficos
Autores principales:	Makrodouli, Eleni, Oikonomou, Eftychia, Koc, Michal, Andera, Ladislav, Sasazuki, Takehiko, Shirasawa, Senji, Pintzas, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189908/ https://www.ncbi.nlm.nih.gov/pubmed/21943101 http://dx.doi.org/10.1186/1476-4598-10-118

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