EBV-gp350 Confers B-Cell Tropism to Tailored Exosomes and Is a Neo-Antigen in Normal and Malignant B Cells—A New Option for the Treatment of B-CLL

gp350, the major envelope protein of Epstein-Barr-Virus, confers B-cell tropism to the virus by interacting with the B lineage marker CD21. Here we utilize gp350 to generate tailored exosomes with an identical tropism. These exosomes can be used for the targeted co-transfer of functional proteins to...

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Detalles Bibliográficos
Autores principales: Ruiss, Romana, Jochum, Simon, Mocikat, Ralph, Hammerschmidt, Wolfgang, Zeidler, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189918/
https://www.ncbi.nlm.nih.gov/pubmed/22022385
http://dx.doi.org/10.1371/journal.pone.0025294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189918/
https://www.ncbi.nlm.nih.gov/pubmed/22022385
http://dx.doi.org/10.1371/journal.pone.0025294

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