False Homozygosity Results in HLA Genotyping due to Loss of Chromosome 6 in a Patient with Acute Lymphoblastic Leukemia

Loss of heterozygosity (LOH) in chromosome 6p has been reported in a number of tumors and some hematologic malignancies, including ALL. LOH in chromosome 6p, on which the HLA genes are located, can give rise to false homozygosity results in HLA genotyping of patients with hematologic malignancies. H...

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Detalles Bibliográficos
Autores principales: Park, Hyewon, Hyun, Jungwon, Park, Sung Sup, Park, Myoung Hee, Song, Eun Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190013/
https://www.ncbi.nlm.nih.gov/pubmed/22016688
http://dx.doi.org/10.3343/kjlm.2011.31.4.302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190013/
https://www.ncbi.nlm.nih.gov/pubmed/22016688
http://dx.doi.org/10.3343/kjlm.2011.31.4.302

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